Islet amyloid polypeptide cytotoxicity directly correlates with amyloidogenicity

SERF, a tiny well conserved protein accelerates amyloid formation via fuzzy complex formation

Biomarker analysis in brain-derived exosomes for improved diagnosis and progression-monitoring of neurodegenerative diseases

Design and early insights of the AREPAS (A Role for Evaluation of PET Amyloid Status) study

Theoretical and computational analysis of the amyloid aggregation kinetics

Are functional and pathological forms of alpha-synuclein so different?

Elucidating the mechanism of immunoglobulin light chain amyloid aggregation

Analysis of amyloid fibril structures by cryo-EM

Which amyloid conformations are propagated in cells?

What is the role of metabolites in amyloid disease?

Whole-brain proton MR spectroscopic imaging and diffusion kurtosis imaging in Alzheimer’s disease

Amyloidogenic nanoparticles in blood serum of patients with Alzheimer´s disease

Interference into aggregation with small molecules

Structural basis for action of serum amyloid a in lipid transport and acute-phase response

Glomerular and vascular amyloidogenesis: The role of mesangial cells and pericytes in al-amyloidosis

Are the bio-molecular traits of fibrils grown in vitro related to the fibrils formed in disease?

Mitochondrial dysfunction and proteostasis in neurodegenerative disease

Amyloid oligomers cross-seeding; How specific is it? What potential implications for therapeutic approaches?

What is the role of insulin on the amyloid aggregation of human islet amyloid polypeptide and its mutants?

Can inhibitors of IAPP aggregation act via a different mechanism depending on whether or not membranes are present?

What is the mechanism of Huntington misfolding? Can we develop tools to monitor and inhibit it?

The lipid-chaperone hypothesis: May amylin, a-synuclein and Aβ have a common molecular mechanism in membrane damage?

Is it amyloid? How do you determine secondary structure in cells?

Innovating high-resolution novel imaging approaches to elucidate mechanisms of prion-like spreading of neurodegenerative disease

What are the structural determinants of amyloid cross-seeding?

Engineered peptides for total degradation of Amyloid

How does Aβ self-aggregate on and exert toxicity against neuronal cells?

What is the molecular basis of Aβ assembly toxicity?

Brain-seeded Aβ oligomers and fibrils

Multitarget proteostasis rescuers: a promising venue in amyloid therapy?

The interplay between metals, peptides and amyloids: mechanisms and therapeutic strategies

Toxicity and characteristics of monomer vs. fibril-derived oligomers

Electron and NMR crystallography to probe amyloid fibers

What secondary structure should be mimicked in peptide derivatives to inhibit the aggregation of amyloid proteins? Helix or β-hairpin?

Are computational techniques useful in designing of drugs for amyloid diseases?

Can we target Aβ oligomers for early diagnosis of Alzheimer's disease?

Islet amyloid induced β-cell death from molecular biophysics to therapeutic applications

Probing the mechanisms of amyloid-β fibril formation by NMR

How do lipid interfaces affect Aβ oligomer generation?

How do small molecules, peptides and chaperones interfere with protein aggregation? - An NMR perspective

Can studying interaction of metal-ion with amyloid-β impact development of ESR spin labeling?

Amyloid aggregation simulations: what can we learn from them?

Amyloid fibrils from the N-terminal prion protein fragment as a model for studying the mechanism of prion propagation and transmissibility barriers

Role of water in protein aggregation and amyloid polymorphism

Amyloid pathology at the neurovascular unit

Rare 3-O-sulfation of heparan sulfate enhances tau interaction, cellular uptake and seeding

Where is the toxicity of Aβ in cells?

Do the individual amyloid aggregates follow the prion model?

Can fluorescent probes aid in antemortem diagnosis of amyloid-associated diseases?

Why are the populations of amyloid oligomers so high? And how we might use that information to design a mouse model?

Are all aggregates created equal? Probing the biochemical and cellular properties of aggregates in vivo

How does disease phenotype correlate with protein structure?